Background: Congenital ichthyoses comprises various specific genetic diseases and can range from mild to very severe presentation.Furthermore, these may be associated with various syndromes.There is scanty data regarding the demographic profile and clinical features of patients with congenital ichthyosis in India.Aims and Objectives: The aim is to
Abstract RNA-binding proteins (RBPs) modulate all aspects of RNA metabolism, but a comprehensive picture of RBP expression Conditioner across tissues is lacking.Here, we describe our development of the method we call HARD-AP that robustly retrieves RBPs and tightly associated RNA regulatory complexes from cultured cells and fresh tissues.We success
Reconstructed human adipose tissues represent novel tools available to perform in vitro pharmaco-toxicological studies.We used adipose-derived human stromal/stem cells to reconstruct, using tissue engineering techniques, such an adipose tridimensional model.To determine to what extent the in vitro model is representative of its native counterpart,
Autumn irrigation is a key measure for alleviating soil salinity and promoting sustainable agricultural development in the Hetao Irrigation district; however, only a part of farmland is irrigated in autumn during the non-growth period of crops, which leads to the redistribution of soil water and salt between autumn-irrigated land (AIL) and adjacent
An epidemic of Severe Acute Respiratory Syndrome (SARS) led Cardamon to the identification of an associated coronavirus, SARS-CoV.This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling.Thus, n